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Prostate Cancer Discoveries Digest

Welcome to your monthly summary of the notable research studies and developments that help provide greater insight into prostate cancer causes, treatments, outcomes, and survivorship.

Prostate Cancer Discoveries Digest

Welcome to the October edition of ZERO’s Prostate Cancer Discoveries Digest! The latest information on treatment, diagnostics, outcomes, and more has been pulled from the headlines and delivered straight to your inbox.

ZERO Prostate Cancer does not endorse any particular article or finding that may be featured.

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Health Equity

West African Genetic Ancestry, Neighborhood Deprivation, and Prostate Cancer

The physical, economic, and social conditions of neighborhoods have long been recognized as significant factors associated with cancer outcomes in racially and ethnically diverse populations, and researchers aimed to understand better how neighborhood deprivation affects prostate cancer outcomes.

» Full Article from JAMA Network

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Treatment

Study Solves Testosterone's Paradoxical Effects in Prostate Cancer

Researchers at Duke University help uncover how bi-polar androgen therapy, or BAT, works and which patients are likely to respond to this type of treatment.

» Full Article from Duke Health

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Outcomes

Impact of Different Visceral Metastatic Sites on Survival in Metastatic Prostate Cancer Patients

In a study of nearly 60,000 prostate cancer patients, researchers reviewed trends in overall survival (OS) by location of metastatic disease - bone, lung, liver, and brain - and by race.

» Full Article from PLOS

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Diagnostics

MRI Accuracy for Recurrence After Partial Gland Ablation with HIFU for Localized Prostate Cancer

Researchers find the diagnostic accuracy of MRI for finding clinically significant prostate cancer recurrence after partial gland ablation with HIFU to be challenging.

» Full Article at Nature

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Treatment

NSD1/2 May Serve as Potential Therapeutic Targets in Prostate Cancer

Two new targets, NSD1 and NSD2, have been identified as viable targets in the treatment of advanced prostate cancer and could, in the future, be combined with FDA-approved androgen receptor antagonists.

» Full Article at Urology Times

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Diagnostics

Northwestern Medicine Study Advocates for Alternative Biopsy Approach for Detecting Prostate Cancer

More than 850 people with suspected prostate cancer were randomized, with half undergoing transperineal prostate biopsy and half undergoing transrectal biopsy being studied for infection, the detection of high-grade cancer, and other complications.

» Full Article from Newsroom

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Diagnostics

Whole-Body Magnetic Resonance Imaging for Staging Patients with High-Risk Prostate Cancer

In this study, whole-body MRI was compared to CT and bone scans in newly diagnosed patients with high-risk prostate cancer.

» Full Article at Nature

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Genetics & Genomics

Prostate Cancer Genetic Testing Lagging Despite Benefits

A study published in JAMA Oncology revealed that only 37% of metastatic prostate cancer patients underwent genetic testing despite national guidelines that recommend it for these patients.

» Full Article at Renal+Urology News

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ZERO Prostate Cancer provides this informational roundup as a resource; it is not intended to take the place of medical professionals or the recommendations of your healthcare team. Consult your healthcare team if you have questions about your specific treatment plan.

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