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Treatments for Metastatic and Advanced Prostate Cancer

When cancer has spread outside of the prostate, there is no cure but there are treatments to slow its growth and improve quality of life. Learn about the major types of therapies, tools to help identify what options is right for you, and updates on new treatments.

Elderly man looking at bottles with pills

Patients with Stage 4 (IV) metastatic prostate cancer often need a whole-body approach to treatment, using "systemic" therapies that travel throughout the body to target cancer that has spread. These therapies may be combined into "doublet" (two concurrent treatments) or "triplet" therapies.

While Stage 3 (III) prostate cancer has also advanced to spread outside of the prostate, it's still in the surrounding tissue and bone, and is often addressed with localized treatment options similar to those used in early-stage disease.

What's the best treatment for advanced prostate cancer?

Multiple types of advanced prostate cancer therapies exist, with therapies that address pain caused by metastasis, strengthen the bones, slow the spread of disease, and improve quality of life. Treatment decisions ultimately come down to your specific diagnosis, personal values, and goals, so it's important to learn as much as you can, including which questions to ask your doctor about your treatment options.

Treatment options for advanced prostate cancer

A systemic therapy is any kind of treatment that targets or travels through the entire body. Some work by removing the hormones that fuel tumor growth, others activate your body's natural defences, or use a range of approaches to attack the cancer directly.

Learn more about each of the types of treatment below, or take a look at a long list of pharmaceuticals that are prescribed for prostate cancer.

A portrait of Euvon Jones, a prostate cancer patient, and his wife, Janet, who serves as his caregiver.

Want help finding the best treatment for you?

Use our Interactive Decision Support Tool, developed in partnership with Clinical Care Options! This tool provides you with expert guidance on treatment options for advanced prostate cancer, based on characteristics you enter. Discover what’s available so you can work with your care team to make the right choices together. 

Headshot of Dr. Alicia Morgans

Treatment updates for advanced prostate cancer

Dr. Alicia Morgans provides an overview of treatment advances and options for metastatic prostate cancer.

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