Prostate Cancer Drugs & Diagnostic Imaging Agents

This chart includes a full list of drugs, therapies, palliatives, and imaging agents used in identifying and treating prostate cancer. To view this list by the clinical name instead of the brand, scroll down the page or click a link at the top to jump directly to a form of treatment.

ZERO Prostate Cancer does not endorse specific treatments. Always consult with your doctor before entering into any drug program.

While we have done our best to compile the latest information on FDA-approved medications and diagnostic imaging agents, the research community continues to find tools for prostate cancer, and the medical community continues to evolve its understanding of the disease. Be sure to subscribe to ZERO's monthly research newsletter to get the latest updates.

Common Treatments & Diagnostic Agents

Brand	Clinical Name	Type	Delivery Method	Key Links	Generic Available?
Akeega	Niraparib and abiraterone acetate			Info & Side Effects Financial Aid
Axumin	Fluciclovine F 18			Info & Side Effects Financial Aid
Casodex	Bicalutamide			Info & Side Effects	Bicalutamide
Camcevi	Leuprolide Mesylate			Info & Side Effects Financial Aid
Cisplatin	Cisplatin			Info & Side Effects	Cisplatin
Eligard	Leuprolide			Info & Side Effects
Erleada	Apalutamide			Info & Side Effects Financial Aid
Eulexin	Flutamide			Info & Side Effects	Flutamide
Firmagon	Degarelix			Info & Side Effects
Illuccix	Gallium (Ga) 68 PSMA-11			Info & Side Effects Financial Aid
Jevtana	Cabazitaxel			Info & Side Effects Financial Aid	Cabazitaxel
Keytruda	Pembroluzumab			Info & Side Effects Financial Aid
Locametz	Gallium (Ga) 68 PSMA-11			Info & Side Effects Financial Aid
Lupron Depot	Leuprolide			Info & Side Effects Financial Aid
Lynparza	Olaparib			Info & Side Effects Financial Aid
Nilandron	Nilutamide			Info & Side Effects	Nilutamide
Novantrone	Mitoxantrone			Info & Side Effects	Mitoxantrone
Nubeqa	Darolutamide			Info & Side Effects Financial Aid
Orgovyx	Relugolix			Info & Side Effects Financial Aid
Paraplatin	Carboplatin			Info & Side Effects	Carboplatin
Pluvicto	Lutetium Lu 177 vipivotide tetraxetan			Info & Side Effects Financial Aid
Posluma	Flotufolastat F 18			Info & Side Effects
Provenge	Sipuleucel-T			Info & Side Effects Financial Aid
Pylarify	Piflufolastat F 18			Info & Side Effects Financial Aid
Rubraca	Rucaparib			Info, Side Effects, & Financial Aid
Talzenna	Talazoparib			Info & Side Effects Financial Aid
Taxotere	Docetaxel			Info & Side Effects	Docetaxel
Trelstar	Triptorelin			Info & Side Effects
Vantas	Histrelin			Info & Side Effects
Xgeva	Denosumab			Info & Side Effects Financial Aid
Xofigo	Radium-223			Info & Side Effects Financial Aid
Xtandi	Enzalutamide			Info & Side Effects Financial Aid
Yonsa	Abiraterone (abiraterone acetate)			Info & Side Effects Financial Aid
Zoladex	Goserelin			Info & Side Effects Financial Aid
Zometa	Zolendronic acid			Info & Side Effects	Zolendronic acid
Zytiga	Abiraterone Acetate			Info & Side Effects Financial Aid	Abiraterone Acetate

* for more information on FDA-approved drugs for prostate cancer, visit the National Cancer Institute.

Hormone Therapy

Generally used to stop the release of testosterone, or to prevent it from acting on prostate cells. Learn more about how hormone therapies work and are distinct from other forms of treatment.

Abiraterone (abiraterone acetate)

Treatment Type: anti-androgen / novel hormone therapy 
Delivery Method: Oral 
Additional Treatment Information: 
Used to treat metastatic prostate cancer. Different brands may have different indications. 

Consumer Brand: Yonsa

Yonsa is approved along with a steroid to treat metastatic prostate cancer that is hormone-resistant (mHRPC), also known as "castrate-resistant," (mCRPC) disease.

• Manufacturer Link: Yonsa drug information, side effects
• Manufacturer Link: Yonsa financial assistance

Consumer Brand: Zytiga

Zytiga is approved to treat metastatic prostate cancer that is hormone-resistant (mHRPC), also known as "castrate-resistant," (mCRPC) disease.

Zytiga is also approved along with androgen deprivation therapy (ADT) to treat metastatic prostate cancer that is hormone-sensitive (mHSPC), also known as "castrate-sensitive," (mCSPC).

• Manufacturer Link: Zytiga drug information and side effects
• Manufacturer Link: Zytiga financial assistance

Apalutamide

Treatment Type: anti-androgen / novel hormone therapy
Delivery Method: Oral
Additional Treatment Information:
Used along with androgen deprivation therapy (ADT) to treat metastatic hormone-sensitive prostate cancer (mHSPC). 

It is also used to treat prostate cancer that has not metastasized and is hormone-resistant (nmHRPC), also known as non-metastatic castrate-resistant prostate cancer (nmCRPC).

Consumer Brand: Erleada

• Manufacturer Link: Erleada drug information, side effects
• Manufacturer Link: Erleada Financial Assistance

Bicalutamide

Treatment Type: Hormone therapy 
Delivery Method: Oral 
Additional Treatment Information: 
Used with LHRH agonists to treat metastatic prostate cancer

Consumer Brand: Casodex

• Manufacturer Link: Casodex drug information, side effects

Darolutamide

Treatment Type: Hormone therapy 
Delivery Method: Oral 
Additional Treatment Information: 
Used along with ADT to treat non-metastatic prostate cancer that is hormone-resistant (nmHRPC), also known as castrate-resistant (nmCRPC). 

It is also used along with ADT and docetaxel to treat metastatic prostate cancer that is hormone-sensitive (mHSPC), also known as castrate-sensitive (mCSPC). 

Consumer Brand: Nubeqa

• Manufacturer Link: Nubeqa drug information, side effects
• Manufacturer Link: Nubeqa Financial Assistance

Degarelix

Treatment Type: Hormone therapy 
Delivery Method: Injection 
Additional Treatment Information: 
Used to treat advanced prostate cancer.

Consumer Brand: Firmagon

• Manufacturer Link: Firmagon drug information, side effects

Enzalutamide

Treatment Type: Hormone therapy 
Delivery Method: Oral 
Additional Treatment Information: 
Used to treat prostate cancer that is hormone-resistant (HRPC), also known as castrate-resistant (CRPC).

It is also used along with ADT to treat metastatic prostate cancer that is hormone-sensitive (mHSPC), also known as castrate-sensitive (mCSPC).

It is also used to treat non-metastatic prostate cancer that is hormone-sensitive (nmHSPC), also known as castrate-sensitive (nmCSPC, and is in biochemical recurrence and at high risk for metastasis.

Consumer Brand: Xtandi

• Manufacturer Link: Xtandi drug information, side effects
• Manufacturer Link: Xtandi Financial Assistance

Flutamide

Treatment Type: Hormone therapy 
Delivery Method: Oral 
Additional Treatment Information: 
Used with LHRH agonists to treat locally advanced or metastatic prostate cancer.

Consumer Brand: Eulexin

• Manufacturer Link: Eulexin drug information, side effects

Goserelin

Treatment Type: Hormone therapy 
Delivery Method: Injection 
Additional Treatment Information: 
Used with flutamide and radiation therapy to treat localized prostate cancer.

It is also used as a palliative treatment in advanced prostate cancer.

Consumer Brand: Zoladex

• Manufacturer Link: Zoladex drug information, side effects
• Manufacturer Link: Zoladex Financial Assistance

Histrelin

Treatment Type: Hormone therapy 
Delivery Method: Implant 
Additional Treatment Information: 
Used to treat advanced prostate cancer.

Consumer Brand: Vantas

• Manufacturer Link: Vantas drug information, side effects

Leuprolide Acetate

Treatment Type: Hormone therapy  
Delivery Method: Injection  
Additional Treatment Information:  
Used as a palliative treatment of advanced prostate cancer.

Consumer Brand: Eligard

• Manufacturer Link: Eligard drug information, side effects

Consumer Brand: Lupron Depot

• Manufacturer Link: Lupron Depot drug information, side effects
• Manufacturer Link: Lupron Depot financial assistance

Leuprolide Mesylate

Treatment Type: Hormone therapy 
Delivery Method: Injection 
Additional Treatment Information: 
Used to treat advanced prostate cancer.

Consumer Brand: Camcevi

• Manufacturer Link: Camcevi drug information, side effects
• Manufacturer Link: Camcevi financial assistance

Nilutamide

Treatment Type: Hormone therapy 
Delivery Method: Oral 
Additional Treatment Information: 
Used with LHRH agonists to treat metastatic prostate cancer.

Consumer Brand: Nilandron

• Manufacturer Link: Nilandron drug information, side effects

Relugolix

Treatment Type: Hormone therapy 
Delivery Method: Oral 
Additional Treatment Information: 
Approved to treat advanced prostate cancer.

Consumer Brand: Orgovyx

• Manufacturer Link: Orgovyx drug information, side effects
• Manufacturer Link: Orgovyx Financial Assistance

Triptorelin

Treatment Type: Hormone therapy 
Delivery Method: Injection 
Additional Treatment Information: 
Used to treat advanced prostate cancer.

Consumer Brand: Trelstar

• Manufacturer Link: Trelstar drug information, side effects

Chemotherapy

Chemo travels through the bloodstream to find and kill cancer cells. Because it is a systemic treatment (meaning it affects the whole body, including healthy cells), it can cause significant side effects. Learn more about how chemotherapy works and is distinct from other forms of treatment.

Cabazitaxel

Treatment Type: Chemotherapy 
Delivery Method: Infusion 
Additional Treatment Information: 
metastatic prostate cancer that is hormone-resistant (mHRPC), also known as castrate-resistant (mCRPC), and has already been treated with docetaxel (chemotherapy)

Consumer Brand: Jevtana

• Manufacturer Link: Jevtana drug information, side effects
• Manufacturer Link: Jevtana Financial Assistance

Carboplatin

Treatment Type: Chemotherapy 
Delivery Method: Infusion 
Additional Treatment Information: 
used in combination with docetaxel or cabazitaxel in some aggressive metastatic prostate cancers

Consumer Brand: Paraplatin

• Manufacturer Link: Paraplatin drug information, side effects

Cisplatin

Treatment Type: Chemotherapy 
Delivery Method: Infusion 
Additional Treatment Information: 
used in combination with docetaxel or cabazitaxel in some aggressive metastatic prostate cancers

Consumer Brand: Cisplatin (generic)

• Manufacturer Link: Cisplatin (generic) drug information, side effects

Docetaxel

Treatment Type: Chemotherapy 
Delivery Method: Infusion 
Additional Treatment Information: 
metastatic prostate cancer that is hormone-resistant (mHRPC), also known as castrate-resistant (mCRPC)

Consumer Brand: Taxotere

• Manufacturer Link: Taxotere drug information, side effects

Mitoxantrone

Treatment Type: Chemotherapy 
Delivery Method: Infusion 
Additional Treatment Information: 
metastatic prostate cancer that is hormone-resistant (mHRPC), also known as castrate-resistant (mCRPC)

Consumer Brand: Novantrone

• Manufacturer Link: Novantrone drug information, side effects

Targeted Therapies

This class of treatments identify a particular genetic component of prostate cancer tumors, and interfere with the specific molecules that drive the growth of the tumor. Learn more about how targeted therapies work and are distinct from other forms of treatment.

Lutetium Lu 177 vipivotide tetraxetan

Treatment Type: Targeted therapy 
Delivery Method: Injection 
Additional Treatment Information: 
delivers radiation directly to PSMA positive (+) cells prostate cancer that overproduces PSMA and is hormone-resistant (mHRPC), also known as castrate-resistant (mCRPC).

Consumer Brand: Pluvicto

• Manufacturer Link: Pluvicto drug information, side effects
• Manufacturer Link: Pluvicto Financial Assistance

Niraparib and abiraterone acetate

Treatment Type: Targeted therapy 
Delivery Method: Oral 
Additional Treatment Information: 
Combination drug used to treat those with a BRCA gene mutation and metastatic prostate cancer that is hormone-resistant (mHRPC), also known as castrate-resistant (mCRPC)

Consumer Brand: Akeega

• Manufacturer Link: Akeega drug information, side effects
• Manufacturer Link: Akeega Financial Assistance

Olaparib

Treatment Type: Targeted therapy 
Delivery Method: Oral 
Additional Treatment Information: 
BRCA gene mutation & metastatic prostate cancer that is hormone-resistant (mHRPC), also known as castrate-resistant (mCRPC); used by itself or in combination with abiraterone

Consumer Brand: Lynparza

• Manufacturer Link: Lynparza drug information, side effects
• Manufacturer Link: Lynparza Financial Assistance

Rucaparib

Treatment Type: Targeted therapy 
Delivery Method: Oral 
Additional Treatment Information: 
BRCA gene mutation & metastatic prostate cancer that is hormone-resistant (mHRPC), also known as castrate-resistant (mCRPC)

Consumer Brand: Rubraca

• Manufacturer Link: Rubraca drug information, side effects, and financial assistance
• Manufacturer Link: Rubraca Financial Assistance (pdf)

Talazoparib

Treatment Type: Targeted therapy 
Delivery Method: Oral 
Additional Treatment Information: 
HRR (homologous recombination repair) gene mutation & metastatic prostate cancer that is hormone-resistant (mHRPC), also known as castrate-resistant (mCRPC); used only in combination with enzalutamide

Consumer Brand: Talzenna

• Manufacturer Link: Talzenna drug information, side effects
• Manufacturer Link: Talzenna Financial Assistance

Immunotherapy (Biologic Therapies)

A whole-body treatment that attempts to activate your immune system so that it will seek and destroy cancer cells, just as it does with other forms of illness within the body. Some forms of immunotherapy are created in a lab, others work with materials already in your body. Learn more about how immunotherapies work and are distinct from other forms of treatment.

Pembroluzumab

Treatment Type: Immunotherapy 
Delivery Method: Injection 
Additional Treatment Information: 
for metastatic cancer patients that have microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) tumors, as determined by an FDA-approved biomarker test, that has progressed following prior treatment and with no satisfactory alternative treatment options

Consumer Brand: Keytruda

• Manufacturer Link: Keytruda drug information, side effects
• Manufacturer Link: Keytruda Financial Assistance

Sipuleucel-T

Treatment Type: Immunotherapy 
Delivery Method: Infusion 
Additional Treatment Information: 
metastatic prostate cancer that is hormone-resistant (mHRPC), also known as castrate-resistant (mCRPC)

Consumer Brand: Provenge

• Manufacturer Link: Provenge drug information, side effects
• Manufacturer Link: Provenge Financial Assistance

Radio-pharmaceuticals

Radioactive treatments that are injected into the body, spreading through the bloodstream and targeting cancer that has spread to the bones. Learn more about how radio-pharmaceuticals work and are distinct from other forms of treatment.

Radium-223

Treatment Type: Radiopharmaceutical 
Delivery Method: Injection 
Additional Treatment Information: 
bone metastases

Consumer Brand: Xofigo

• Manufacturer Link: Xofigo drug information, side effects
• Manufacturer Link: Xofigo Financial Assistance

Lutetium Lu 177 vipivotide tetraxetan

Treatment Type: Radiopharmaceutical
Delivery Method: Injection 
Additional Treatment Information: 
Pluvicto is both a targeted therapy and a radiopharmaceutical, see its details in the "Targeted Therapies" section of this page.

Consumer Brand: Pluvicto

Bone Targeting Agents

Treatments meant to strengthen the bones, helping offset the damage and pain caused by prostate cancer that has spread through the body. Learn more about how bone targeting agents work and are distinct from other forms of treatment.

Denosumab

Treatment Type: Bone Targeting Agents 
Delivery Method: Injection 
Additional Treatment Information: 
bone metastases

Consumer Brand: Xgeva

• Manufacturer Link: Xgeva drug information, side effects
• Manufacturer Link: Xgeva Financial Assistance

Zolendronic acid

Treatment Type: Bone Targeting Agents 
Delivery Method: Infusion 
Additional Treatment Information: 
bone metastases

Consumer Brand: Zometa

• Manufacturer Link: Zometa drug information, side effects

Diagnostic/Imaging Agents

Some forms of bone scans and full-body imaging work with chemicals that are absorbed by tissue, making it clear when tumors have spread. Learn more about how various imaging techniques work to identify prostate cancer in the body.

Flotufolastat F 18

Treatment Type: Diagnostic Imaging Agents 
Delivery Method: Injection 
Additional Treatment Information: 
detects PSMA positive lesions; used with PET imaging for suspected metastasis or suspected recurrence

Consumer Brand: Posluma

• Manufacturer Link: Posluma drug information, side effects

Fluciclovine F 18

Treatment Type: Diagnostic Imaging Agents 
Delivery Method: Injection 
Additional Treatment Information: 
used with PET imaging for men with prior treatment for PCa and rising PSA levels

Consumer Brand: Axumin

• Manufacturer Link: Axumin drug information, side effects
• Manufacturer Link: Axumin Financial Assistance

Gallium (Ga) 68 PSMA-11

Treatment Type: Diagnostic Imaging Agents  
Delivery Method: Injection  
Additional Treatment Information:  
Detects PSMA positive lesions; used with PET imaging for suspected metastasis or suspected recurrence.

Consumer Brand: Illuccix

• Manufacturer Link: Illuccix drug information, side effects
• Manufacturer Link: Illuccix Financial Assistance

Consumer Brand: Locametz

• Manufacturer Link: Locametz drug information, side effects
• Manufacturer Link: Locametz Financial Assistance

Piflufolastat F 18

Treatment Type: Diagnostic Imaging Agents 
Delivery Method: Injection 
Additional Treatment Information: 
detects PSMA positive lesions; used with PET imaging for suspected metastasis or suspected recurrence

Consumer Brand: Pylarify

• Manufacturer Link: Pylarify drug information, side effects
• Manufacturer Link: Pylarify Financial Assistance