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Prostate Cancer Discoveries Digest

Welcome to your monthly summary of the notable research studies and developments that help provide greater insight into prostate cancer causes, treatments, outcomes, and survivorship.

Prostate Cancer Discoveries Digest

The prostate cancer landscape is rapidly changing. This featured content is meant to provide an update on the latest in diagnosis, treatment, side effect management, and survivorship. ZERO Prostate Cancer does not endorse any particular article or finding that may be featured.

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Treatment

Prostate Cancer: Adjuvant Radiotherapy With 6 Months of ADT vs No ADT

Metastasis-free survival was not significantly improved with 6 months of ADT v no ADT plus adjuvant radiotherapy.

» Full article on The ASCO Post

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Screening

Access to Prostate-Specific Antigen Testing and Mortality Among Men With Prostate Cancer

Men living in US counties with a higher prevalence of PSA screening are less likely to have advanced prostate cancer and to die from it.

» Full article on JAMA Network Open

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Survivorship

First results from Europa Uomo's innovative study into couples' quality of life

A survey of 1,135 caregivers of those diagnosed with prostate cancer found a striking mismatch between the information partners expect and the information given.

» Full article on Europa Uomo

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Treatment

Active surveillance yields similar outcomes to prostate cancer treatment, 10-year data show

Long-term data recently published in JAMA indicate that active surveillance is an effective alternative to immediate surgery or radiation for patients with favorable-risk prostate cancer.

» Full article on Urology Times

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Treatment

100% BCR-Free at 2 Years: Promising Early Results for High-Risk Prostate Cancer

Early data shows great promise for high-risk, localized prostate cancer.

» Full article on Targeted Oncology

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Treatment

CRISPR Identifies New Genes as Drivers of Prostate Cancer Metastasis

CRISPR (short for "clustered regularly interspaced short palindromic repeats"), technology that research scientists use to selectively modify the DNA of living organisms, has opened potential new avenues for targeted cancer therapies.

» Full article on CRISPR Medicine News

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Treatment

Artificial Intelligence Improves the Ability of Physicians to Identify Prostate Cancer Extent

AI tool may help doctors better deliver focal therapy and lead to changes in clinical treatment decision-making.

» Full article on American Urological Association Journals

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Survivorship

Survival in Patients With De Novo Metastatic Prostate Cancer

A cross-sectional study examining US SEER (Surveillance, Epidemiology, and End Results) and VHA (Veterans Health Administration) data showed that the median overall survival in de novo mHSPC has improved significantly in the US from 2000-2019, particularly in patients younger than 70 years.

» Full article on JAMA Network Open

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Treatments

FDA awards fast track designation to BNT324/DB-1311 in mCRPC

The FDA has granted a fast track designation to a drug candidate for patients with mCRPC whose tumors have progressed on standard systemic therapy.

» Full article on Urology Times

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Diagnostics

FDA approves FoundationOneLiquid CDx for niraparib/abiraterone in mCRPC

The FDA has approved the liquid biopsy test FoundationOneLiquid CDx for use as a companion diagnostic in identifying patients with BRCA-positive mCRPC who may benefit from treatment with niraparib and abiraterone acetate dual action tablets (Akeega).

» Full article on Urology Times

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ZERO Prostate Cancer provides this information as a service. It is not intended to take the place of medical professionals or the recommendations of your healthcare team. Consult your healthcare team if you have questions about your specific care.

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