Prostate Cancer Discoveries Digest
Welcome to your monthly summary of the notable research studies and developments that help provide greater insight into prostate cancer causes, treatments, outcomes, and survivorship.
Welcome to the April 2025 edition of ZERO's Prostate Cancer Discoveries Digest. The latest information on treatment, diagnostics, side effects, and more has been pulled from the headlines and delivered to your inbox.
Be sure to share this newsletter with your network to ensure that everyone receives the latest information on prostate cancer discoveries.
ZERO Prostate Cancer does not endorse any particular article or finding that may be featured.
FDA Expands Pluvicto's Metastatic Castration-Resistant Prostate Cancer Indication
The FDA has expanded the approval for Pluvicto to include adults with PSMA-positive mCRPC who have been treated with ARPI therapy and are considered appropriate to delay taxane-based chemotherapy.
» Full Article from the U.S. FDA
Microultrasonography-Guided vs. MRI-Guided Biopsy for Prostate Cancer Diagnosis
Results published in JAMA highlight results from a clinical trial in which researchers learned that microultrasonography might provide an alternative to MRI for image-guided prostate biopsy.
» Full Article from JAMA Network
Novel Strategy Could Help Recover Function Following Prostate Cancer Surgery
A new strategy may improve function following surgery for prostate cancer, raising the prospect for significant quality of life improvements.
» Full Article from The ASCO Post
Study Finds Geographic Disparities in MRI Use in Prostate Cancer
Racial disparities in MRI have decreased, but urban-rural and regional disparities persist, with rural areas less likely to utilize MRI, indicating a need for targeted interventions focused on geographical factors, among others.
» Full Article from Urology Times
Males Who Skip Prostate Cancer Screenings Could Face 45% Higher Risk of Death
Although not yet published in a peer-reviewed journal, results from a new study found that 1 in 6 males skipped all of their prostate cancer screening appointments, leading to a 45% higher risk of death from the disease.
» Full Article from Healthline
PSMA PET for Prostate Cancer Diagnosis and Primary Staging Before Definitive Treatment
The diagnostic and staging accuracy of PSMA PET in prostate cancer was examined in a systematic review and meta-analysis to inform biopsy or lymph node dissection reliably.
» Full Article from the National Library of Medicine
Radical Prostatectomy Improves Cancer-Specific Survival in Oligometastatic Prostate Cancer
Surgery reduced the risk of cancer death among men with de novo oligometastatic prostate cancer receiving systemic therapy.
» Full Article from Renal+Urology News
Exercise Can Lessen Fatigue in Prostate Cancer Patients Undergoing ADT
Results from a new study demonstrate that exercise can decrease fatigue, a common side effect, in patients with advanced prostate cancer undergoing ADT.
» Full Article from Clinical Oncology News
Racial Variation in the Advanced Prostate Cancer Genome
Racial differences in the expression of certain prostate cancer driver gene pathways and DNA alterations highlight racial diversity's importance in future genomic profiling and clinical trial efforts.
ZERO Prostate Cancer provides this informational roundup as a resource; it is not intended to replace medical professionals' or your healthcare team's recommendations. Consult your healthcare team if you have questions about your specific treatment plan.
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