Chart: NCCN Guidelines for Early Detection (Age, Risk Factors, PSA Scores)

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Prostate Cancer Early Detection: Age Recommendations and PSA Levels Chart
Age 40-75 Black/African American individuals Those with a family history of cancer and/or known genetic mutation that increases the risk for prostate cancer Age 45-75 Average-risk individuals	Discuss risk and benefits of prostate cancer screening with your doctor.
	Have a baseline PSA and strongly consider a baseline DRE.
	If PSA less than 1 ng/mL and DRE normal (if done), repeat testing every 2 – 4 years.
	If PSA 1 - 3 ng/mL and DRE normal (if done), repeat testing every 1 – 2 years.
	If PSA greater than 3 ng/mL and/or a very suspicious DRE, talk with your doctor about further testing and follow-up.
Age 75+	Talk with your doctor about if prostate cancer screening should continue.
	If PSA less than 4 ng/mL and DRE normal (if done), repeat testing in select patients every 1 – 4 years.
	If PSA greater than 4 ng/mL or a very suspicious DRE, talk with your doctor about further testing and follow-up.

Based on National Comprehensive Cancer Network® Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Prostate Cancer Early Detection 2022.

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