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SEA Stories

Us TOO Prostate Cancer Pathways for Patients & Caregivers – June 23, 2018, Kirkland, WA

Presenting Sponsor: Janssen Oncology
Supporting Sponsors: Bayer, Sanofi Genzyme, Astellas Pfizer, Amgen, Genomic Health, Abbvie, Color
Hosted by: Evergreen Health Medical Center

Guest Speakers:

  • Dr. Jonathan Wright – Medical Director, UWMC Urology Clinic
  • Dr. Brian D. Lawenda – Radiation Oncologist, Northwest Cancer Clinic and 21st Century Oncology
  • Dr. Cobie Whitten – Psycho-Oncology Consultant, Providence Regional Cancer System
  • Katie Stoll, MS, LGC – Executive Director, Genetic Support Foundation
  • Dr. Heather Cheng – Director, Prostate Cancer Genetics Clinic

Hosted by Evergreen Health Medical Center in collaboration with the Us TOO Washington Prostate Cancer Support Groups and the Washington Prostate Cancer Coalition.

View the full video by clicking on the image below; or scroll down to access links to short video segments about specific content presented at the event.

Click any link listed below to go straight to go straight to that segment of the video: (5 Hours, 29 Minutes of Video Content)

  • 0:01 Intro – Chuck Strand, CEO of Us TOO International
  • 6:12 Intro to Dr. Brian D. Lawenda, Radiation Oncologist at Northwest Cancer Clinic and 21st Century Oncology
  • 8:09 PCa Stats Risks, Lifestyle, Diet, Exercise, Stress
  • 13:28 Chronic Inflammation
  • 14:21 Nuclear Factor Kappa B (NF-KB) "The Inflammatory Switch"
  • 16:52 Inflammatory Biomarkers
  • 17:35 High-Sensitivity C Reactive Protein
  • 18:49 The Anti-Inflammatory Diet
  • 21:31 Cancer-Fighting Effects of Phytochemicals
  • 24:00 Carbohydrates
  • 26:28 Obesity
  • 27:23 Insulin
  • 29:17 Healthy Diet
  • 30:31 Physical Activity
  • 32:16 Stress and Anxiety
  • 38:15 Lifestyle
     
  • 41:13 Intro to Dr. Jonathan Wright, Medical Director at UWMC Urology Clinic
  • 42:44 Prostate Cancer 101
  • 45:04 Stats
  • 46:07 Risk Factors
  • 48:50 Diagnosis
  • 49:13 Mortality
  • 50:26 PSA
  • 55:16 DRE
  • 56:22 Biopsy
     
  • 57:43 Intro to Dr. Cobie Whitten, Psycho-Oncology Consultant at Providence Regional Cancer System
  • 58:37 Common Psychosocial Challenges
     
  • 1:14:45 Dr. Wright
  • 1:15:26 Randomized Studies
  • 1:20:45 Comparing Screening Tools
  • 1:21:03 PSA Screening Trials
  • 1:21:32 Biopsy
  • 1:21:48 PSA by Age
  • 1:24:10 Disease State Biomarkers
  • 1:24:43 PCPT Risk Calculator
  • 1:26:26 Gleason Grades and New Grade Group System
  • 1:29:16 The Challenge of Prostate Cancer Management
  • 1:29:53 Disease State Biomarkers
  • 1:31:10 Genomic Testing
  • 1:32:52 Active Surveillance
  • 1:37:35 Obesity and Fatal Prostate Cancer
  • 1:38:49 Exercise and Prostate Cancer
  • 1:44:12 Androgen Deprivation Therapy Affects
  • 1:46:11 Sarcopenia
     
  • 2:1:34 Dr. Cobie Whitten – Deer in Headlights – Psychosocial Effects of Diagnosis
     
  • 2:35:51 Dr. Lawenda
  • 2:36:11 Consensus Based Guidelines for Treatment
  • 2:40:28 MRI
  • 2:42:06 Molecular/Genomic Testing
     
  • 2:46:26 Second Opinion
  • 2:48:43 Genetic Testing
  • 2:50:10 AJCC TNM Staging
  • 2:51:34 MSKCC Pre-Radical RP Nomogram
  • 2:54:30 Radiology Studies
  • 2:55:44 PET Scans
  • 2:58:56 Prostate Cancer Management
  • 2:59:33 HIFU
  • 3:0:18 Cryotherapy
  • 3:1:07 Radiation Techniques
  • 3:7:02 SpaceOAR
  • 3:8:07 Stereotactic Body Radiation Therapy
  • 3:9:43 Brachytherapy
  • 3:12:49 Prostatectomy
  • 3:17:06 Testosterone (Fuel for PCa)
  • 3:17:51 Androgen Deprivation Therapy
  • 3:19:38 ADT with Radiation or After RP
  • 3:20:40 Progression of Prostate Cancer
  • 3:22:33 Androgen Receptor V7
  • 3:24:34 Extent of Metastatic Disease
  • 3:26:48 Castration Naive M1
  • 3:27:22 Anti-Resorptive Bone Therapies
  • 3:28:19 Castration Recurrent M0
  • 3:29:18 Castration Recurrent M1
  • 3:30:07 Radium-223 (Xofigo)
  • 3:31:18 Castration Recurrent M1
  • 3:32:16 Acupuncture for Hot Flashes
  • 3:32:52 Cranberry Extract for Radiation Dysuria
  • 3:33:35 Hyperbaric Oxygen Therapy
  • 3:34:53 Ginseng for Cancer-Related Fatigue
  • 3:35:19 Sleep Problems and Cancer-Related Fatigue
  • 3:36:00 Probiotics for Radiation-Induced Diarrhea
  • 3:36:43 Exercise and Diet
  • 3:37:23 What to Do if Your Treatments Aren't Working
  • 3:37:37 Get More Opinions
  • 3:38:20 Clinical Trials
  • 3:40:06 Assay Directed Treatment
  • 3:41:25 Palliative Care
  • 3:42:02 Hospice Care
     
  • 3:45:05 Dr. Whitten – Living With Uncertainty After Cancer Diagnosis
  • 3:50:02 A Cancer Survivor
  • 3:51:53 Decision Making
  • 3:53:07 Barrier – Fear, Anger, and Stress
  • 3:57:14 Barrier – Difficulty Understanding Complex Health Information
  • 3:57:50 Decision Aids
  • 3:58:01 Stages of Cancer Surviving
  • 4:1:39 Emotional Adjustment
  • 4:2:47 End of Active Treatment
  • 4:9:58 Emotions
  • 4:10:31 Emotional Adjustment
  • 4:11:52 Depression and Cancer
  • 4:12:48 Signs of Depression
  • 4:13:24 Other Signs of High Distress
  • 4:14:39 Past Events and Distress Levels
  • 4:15:17 Relationships
  • 4:18:11 Sexuality and Intimacy
  • 4:19:27 Caregiver Issues
  • 4:21:48 Dimensions of Quality of Life
  • 4:22:14 Coping Strategies
  • 4:30:42 Catalyst for Living
  • 4:32:12 Seeking Help
     
  • 4:33:27 Intro to Dr. Heather H. Cheng, Director of Prostate Cancer Genetics Clinic
  • 4:35:17 Harnessing the Benefits of Genetic Testing
  • 4:38:20 Genetics: Can be Inherited or Cancer-Specific
  • 4:42:24 Some Genes Confer Very High Risk of Cancer
  • 4:42:54 Variants vs. Mutations in Genes
  • 4:45:17 Germline BRCA1 and BRCA2 Mutations Affect Risk of Developing Prostate Cancer
  • 4:46:29 BRCA1/2 Carriers (Female) Have Options for Reducing Risk
  • 4:47:05 Genetic Effects on Cancer Risk are Not Equal
  • 4:48:00 Importance of Family History of Cancer
  • 4:49:07 Germline (Inherited) BRCA2 Mutations
  • 4:51:44 Treatment Biomarkers in Advanced Prostate Cancer
  • 4:52:59 Who Should be Offered Germline Genetic Testing?
  • 4:53:57 BRCA2 Mutations
  • 4:55:50 Barriers to Genetic Testing
  • 4:56:10 Prostate Cancer Genetics Clinic/Pathway
  • 4:59:47 A Shared Vision of Cascading Impact
     
  • 5:1:15 Intro to Katie Stoll, Executive Director of Genetic Support Foundation
  • 5:2:27 Harnessing the Benefits of Genetic Testing
  • 5:4:43 Genetics 101
  • 5:5:03 DNA
  • 5:5:11 Genes
  • 5:5:27 Mutations
  • 5:8:12 Prostate Cancer Risk and Family History
  • 5:8:58 DNA – Repair Genes
  • 5:11:58 Hereditary Cancer – BRCA1/BRCA2
  • 5:12:28 Genetic Tests are Not All the Same
  • 5:17:13 What is Genetic Counseling?