Advanced Prostate Cancer Advanced prostate cancer is cancer that has spread beyond the prostate. Facing advanced, or metastatic, prostate cancer can be scary. Learn more and find support. Jump To Jump To Imaging Treatment Options Additional Resources Clinical Trials Understanding advanced prostate cancerAdvanced prostate cancer is cancer that has spread beyond the prostate. It may also be called Stage III (3) or Stage IV (4) prostate cancer. It can be overwhelming to hear that you or a loved one has advanced prostate cancer. Find out as much information as you can about your cancer so you feel empowered to make the right decisions.The different stages of advanced prostate cancer include:Locally advanced: Cancer has spread beyond the outer layer of the prostate into nearby tissues, such as nearby lymph glands or the seminal vesicles. Locally advanced prostate cancer is referred to as Stage III and is considered non-metastatic.Metastatic: Cancer has spread to other parts of the body, such as the bones, lungs, or liver. This is also referred to as Stage IV prostate cancer.It is also important to understand if your locally advanced or metastatic prostate cancer is responding to hormone therapy. Your prostate cancer may further be defined as:Non-metastatic hormone-sensitive prostate cancer (nmHSPC): Prostate cancer that still responds to hormone therapy and there is no detectable metastases - spread of cancer - upon imaging. It may also be referred to as nmCSPC, or non-metastatic castration-sensitive prostate cancer.Metastatic hormone-sensitive prostate cancer (mHSPC): Prostate cancer that still responds to hormone therapy but has advanced to metastatic stage. It is also referred to as metastatic castration-sensitive prostate cancer (mCSPC).Non-metastatic castration-resistant prostate cancer (nmCRPC): Prostate cancer that has stopped responding to hormone therapy and there is no detectable metastases upon imaging. It may be referred to as non-metastatic hormone-resistant prostate cancer (nmHRPC).Metastatic castration-resistant prostate cancer (mCRPC): Prostate cancer that has stopped responding to hormone therapy and has advanced to metastatic stage. It may be referred to as metastatic hormone-resistant prostate cancer (mHRPC).While there is no cure for metastatic prostate cancer, there is hope to manage the disease effectively through new treatments. These new treatment options can help slow the disease progression and give you more time to live your best life. The importance of imaging for advanced prostate cancerImaging has long been important in determining whether prostate cancer has spread. The discovery of new imaging techniques and agents, such as the PSMA PET scan, make it easier to see prostate cancer cells - even in small amounts - that have traveled outside the prostate to other places in the body. These advances are improving:How a patient’s prognosis, or outcome, is determined.Understanding if a treatment is working.How treatment decisions are made.Learn more about how imaging can provide more information for you and your doctor. Play Video Close Meet Darrell Wilson, an advanced prostate cancer patient As an advanced prostate cancer patient, Darrell Wilson knows firsthand that knowledge is power. There are many treatment options available to fight prostate cancer, and it’s important that patients and their caregivers understand the options, including the new ones coming down the pipe. As Darrell shares, that’s what gives him hope. Treatment for advanced prostate cancer Learn all you can about your prostate cancer treatment options and talk to your doctor and loved ones before making your treatment decision. Check out treatment options Play Video Close Want help finding the best treatment for you? Use our Interactive Decision Support Tool, developed in partnership with Clinical Care Options! This tool provides you with expert guidance on treatment options for advanced prostate cancer, based on characteristics you enter. Discover what’s available so you can work with your care team to make the right choices together. Patient Interactive Treatment Tool Additional resources related to advanced prostate cancer Advanced Prostate Cancer One-Pager (PDF) This free PDF download explains metastatic prostate cancer (stage IV), as well as stage III (locally advanced) disease. Details include terms used to describe the disease, various treatments, statistics, bone health, and living with the disease. Print the one-pager (double-sided) at home, or forward via email. Advanced Prostate Cancer Newsletter An annual review of major developments in advanced prostate cancer research and treatments, along with support opportunities and healthcare expert insights for those living with Stage III and Stage V disease. Questions for Your Doctor Questions to ask your doctor when living with advanced prostate cancer, to make a plan and manage the disease. Advanced prostate cancer has spread to other parts of the body, and is also known as metastatic or stage IV. Treatments for metastatic hormone-sensitive (mHSPC) prostate cancer Learn more about your treatment options for metastatic hormone-sensitive (mHSPC) prostate cancer, developed in partnership with Medscape Oncology. National Comprehensive Cancer Network Patient Resources The NCCN provides many guides and resources for cancer patients and care partners, including for Prostate Cancer: Advanced Stage. Patient Support Helpline Call ZERO360, our free, comprehensive patient support service, if you need help finding insurance, financial, emotional, and other resources. Clinical trials Clinical trials are a great treatment option for advanced prostate cancer patients. Find out if one may be right for you or your loved one. Find a clinical trial
Understanding advanced prostate cancerAdvanced prostate cancer is cancer that has spread beyond the prostate. It may also be called Stage III (3) or Stage IV (4) prostate cancer. It can be overwhelming to hear that you or a loved one has advanced prostate cancer. Find out as much information as you can about your cancer so you feel empowered to make the right decisions.The different stages of advanced prostate cancer include:Locally advanced: Cancer has spread beyond the outer layer of the prostate into nearby tissues, such as nearby lymph glands or the seminal vesicles. Locally advanced prostate cancer is referred to as Stage III and is considered non-metastatic.Metastatic: Cancer has spread to other parts of the body, such as the bones, lungs, or liver. This is also referred to as Stage IV prostate cancer.It is also important to understand if your locally advanced or metastatic prostate cancer is responding to hormone therapy. Your prostate cancer may further be defined as:Non-metastatic hormone-sensitive prostate cancer (nmHSPC): Prostate cancer that still responds to hormone therapy and there is no detectable metastases - spread of cancer - upon imaging. It may also be referred to as nmCSPC, or non-metastatic castration-sensitive prostate cancer.Metastatic hormone-sensitive prostate cancer (mHSPC): Prostate cancer that still responds to hormone therapy but has advanced to metastatic stage. It is also referred to as metastatic castration-sensitive prostate cancer (mCSPC).Non-metastatic castration-resistant prostate cancer (nmCRPC): Prostate cancer that has stopped responding to hormone therapy and there is no detectable metastases upon imaging. It may be referred to as non-metastatic hormone-resistant prostate cancer (nmHRPC).Metastatic castration-resistant prostate cancer (mCRPC): Prostate cancer that has stopped responding to hormone therapy and has advanced to metastatic stage. It may be referred to as metastatic hormone-resistant prostate cancer (mHRPC).While there is no cure for metastatic prostate cancer, there is hope to manage the disease effectively through new treatments. These new treatment options can help slow the disease progression and give you more time to live your best life.
The importance of imaging for advanced prostate cancerImaging has long been important in determining whether prostate cancer has spread. The discovery of new imaging techniques and agents, such as the PSMA PET scan, make it easier to see prostate cancer cells - even in small amounts - that have traveled outside the prostate to other places in the body. These advances are improving:How a patient’s prognosis, or outcome, is determined.Understanding if a treatment is working.How treatment decisions are made.Learn more about how imaging can provide more information for you and your doctor.
Play Video Close Meet Darrell Wilson, an advanced prostate cancer patient As an advanced prostate cancer patient, Darrell Wilson knows firsthand that knowledge is power. There are many treatment options available to fight prostate cancer, and it’s important that patients and their caregivers understand the options, including the new ones coming down the pipe. As Darrell shares, that’s what gives him hope.
Treatment for advanced prostate cancer Learn all you can about your prostate cancer treatment options and talk to your doctor and loved ones before making your treatment decision. Check out treatment options
Play Video Close Want help finding the best treatment for you? Use our Interactive Decision Support Tool, developed in partnership with Clinical Care Options! This tool provides you with expert guidance on treatment options for advanced prostate cancer, based on characteristics you enter. Discover what’s available so you can work with your care team to make the right choices together. Patient Interactive Treatment Tool
Additional resources related to advanced prostate cancer Advanced Prostate Cancer One-Pager (PDF) This free PDF download explains metastatic prostate cancer (stage IV), as well as stage III (locally advanced) disease. Details include terms used to describe the disease, various treatments, statistics, bone health, and living with the disease. Print the one-pager (double-sided) at home, or forward via email. Advanced Prostate Cancer Newsletter An annual review of major developments in advanced prostate cancer research and treatments, along with support opportunities and healthcare expert insights for those living with Stage III and Stage V disease. Questions for Your Doctor Questions to ask your doctor when living with advanced prostate cancer, to make a plan and manage the disease. Advanced prostate cancer has spread to other parts of the body, and is also known as metastatic or stage IV. Treatments for metastatic hormone-sensitive (mHSPC) prostate cancer Learn more about your treatment options for metastatic hormone-sensitive (mHSPC) prostate cancer, developed in partnership with Medscape Oncology. National Comprehensive Cancer Network Patient Resources The NCCN provides many guides and resources for cancer patients and care partners, including for Prostate Cancer: Advanced Stage. Patient Support Helpline Call ZERO360, our free, comprehensive patient support service, if you need help finding insurance, financial, emotional, and other resources.
Clinical trials Clinical trials are a great treatment option for advanced prostate cancer patients. Find out if one may be right for you or your loved one. Find a clinical trial
