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For Prostate Cancer, Study Identifies How Common Mutation Makes Good Cells Go Bad

A paper in Molecular Cell, showed that the fused prostate proteins engage in an act of molecular piracy, roping a cellular machine called the BAF complex into helping it boot up a gene expression program that would otherwise be silent in normal prostate cells. This, they found, encourages prostate cells’ transformation into cancer cells, and may provide a new opportunity for prostate cancer drug development.
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source: Tom Ulrich - Medical Xpress