While some approaches have matured, others are still in their infancy. We have learned that Active Surveillance is safe in patients with low-risk prostate cancer while patients with high-risk prostate cancer are best served by a multimodality approach including surgery, radiotherapy, and medical management [1, 2]. In patients with moderate-risk prostate cancer, we are balancing our choice between cancer control and cancer cure. While surgery offers a potential cure for the disease, it also harbors a significant probability for morbidity and complications. Hence many men and their partners value not to impair quality of life as a possible trade-off for a definitive cure.